We offer value assignments with reference methods for the following parameters:

Parameter

Reference Reference method

pH

[1] BMS2 (Radiometer)

pCO2

[1] Tonometry

pO2

[1] Tonometry

Na+

[1] FAES (Flame Atomic Emission Spectrophotometry)

K+

[1] FAES (Flame Atomic Emission Spectrophotometry)

Li+

[1] FAES (Flame Atomic Emission Spectrophotometry)

iCa2+

[1] iCa2 (Radiometer)

tCa

[1] AAS (Atomic Absorption Spectrophotometry)

Cl-

[1] Amperometric titration

Glucose

­ YSI or GDH

HbA1c

­ IFCC and DCCT

tHb

[2,3] CNMetHb reference method

Hb-derivatives

[4] Spectrophotometry


[1] Maas AHJ. IFCC Reference Methods for Measurement of pH, Gases and Electrolytes in Blood: Reference Materials. Eur. J. Clin. Chem. Clin. Biochem. 1991;29:253-261.


[2] Zijlstra WG and van Kampen EJ. Standardization of Hemoglobinometry III. Preparation and use of a stable hemiglobincyanide standard. Clinica Chimica Acta (1962);7:96-99.


[3] International Committee for Standardisation in haematology. Recommen-dations for reference method for haemoglobi-nometry in human blood and specifications for interna-tional hemiglobincyanide reference preparation, J. Clin. Pathol. 1978;31: 139-143.


[4] Maas BHA, Buursma A, Ernst RAJ, Maas AHJ and Zijlstra WG. Lyophilized bovine hemoglobin as a possible reference material for the determination of hemoglobin derivatives in human blood.